437628
Lipopolysaccharide
from Salmonella minnesota, , lyophilized, TLR4 signaling stimulator, Calbiochem
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About This Item
UNSPSC Code:
12352201
NACRES:
NA.77
product name
Lipopolysaccharide, Ultra Pure, Salmonella minnesota R595 (Re), Phenol-petroleum ether extracted lipopolysaccharide (LPS) containing ≤0.3% proteins.
Quality Level
form
lyophilized
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
solubility
0.5% triethylamine: 1 mg/mL
water: 1 mg/mL
shipped in
ambient
storage temp.
2-8°C
General description
Phenol-petroleum ether extracted lipopolysaccharide (LPS) containing ≤0.3% proteins. LPS 595 (Re) has been shown to stimulate Toll-like receptor-4 (TLR4), but not TLR2, signaling in human cell lines.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Stimulate Toll-like receptor-4 (TLR4) signaling in human cell lines
Stimulate Toll-like receptor-4 (TLR4) signaling in human cell lines
Product does not compete with ATP.
Reversible: no
Warning
Toxicity: Harmful (C)
Preparation Note
Warming to 37°C with intermittent vortexing or sonication may be required to achieve complete solubilization in H₂O.
Reconstitution
Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 6 months.
Other Notes
Hirschfeld, M., et al. 2000. J. Immunol.165, 618.
Tapping, R.I., et al. 2000. J. Immunol.165, 5780.
Galanos, C., et al. 1969. Eur. J. Biochem.9, 245.
Tapping, R.I., et al. 2000. J. Immunol.165, 5780.
Galanos, C., et al. 1969. Eur. J. Biochem.9, 245.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 2 Oral
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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