428017
Anti-Lamp1 Mouse mAb (LY1C6)
liquid, clone LY1C6, Calbiochem®
Sign Into View Organizational & Contract Pricing
All Photos(1)
Synonym(s):
Anti-Lysosome-Associated Membrane Protein 1
UNSPSC Code:
12352203
NACRES:
NA.41
Recommended Products
biological source
mouse
Quality Level
antibody form
purified antibody
antibody product type
primary antibodies
clone
LY1C6, monoclonal
form
liquid
contains
≤0.09% sodium azide as preservative
species reactivity
rat
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
avoid repeated freeze/thaw cycles
isotype
IgG1
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
rat ... Lamp1(25328)
General description
Protein G purified mouse monoclonal antibody. Recognizes the ~120 kDa Lamp1 protein.
Recognizes the ~120 kDa Lamp1 protein.
This Anti-Lamp1 Mouse mAb (LY1C6) is validated for use in Immunoblotting, Immunocytochemistry, Immunofluorescence, Immunoprecipitation for the detection of Lamp1.
Immunogen
Rat
rat liver lysosomal membranes
Application
Immunoblotting (1 µg/ml, chemiluminescence)
Immunocytochemistry (1:100)
Immunofluorescence (see comments)
Immunoprecipitation (see comments)
Immunocytochemistry (1:100)
Immunofluorescence (see comments)
Immunoprecipitation (see comments)
Packaging
Please refer to vial label for lot-specific concentration.
Warning
Toxicity: Standard Handling (A)
Physical form
In PBS containing 50% glycerol, pH 7.2.
Reconstitution
Following initial thaw, aliquot and freeze (-20°C).
Analysis Note
Positive Control
CHO-K1 cells
CHO-K1 cells
Other Notes
Kannan, K. et al. 1996. Cell Immunol.171, 10.
Rohrer, J., et al. 1996. J. Cell Biol. 132, 565.
Howe et al. 1988. PNAS85, 7577.
Lewis et al. 1985. J. Cell Biol.100, 1839.
Rohrer, J., et al. 1996. J. Cell Biol. 132, 565.
Howe et al. 1988. PNAS85, 7577.
Lewis et al. 1985. J. Cell Biol.100, 1839.
This antibody has also been reported to work for immunofluorescence and immunoprecipitation. Antibody should be titrated for optimal results in individual systems.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Arvind Chhabra et al.
European journal of immunology, 34(10), 2824-2833 (2004-09-16)
Dendritic cells (DC) capture antigens from apoptotic and/or necrotic tumor cells and cross-present them to T cells, and various ways of delivering tumor antigens to DC in vitro and in vivo are being pursued. Since fusions of antigenic proteins with
María Morell et al.
EBioMedicine, 76, 103808-103808 (2022-01-23)
Type I IFN (IFN-I) is a family of cytokines involved in the pathogenesis of autoimmune and autoinflammatory diseases such as psoriasis. SIDT1 is an ER-resident protein expressed in the lymphoid lineage, and involved in anti-viral IFN-I responses in vivo, through
Vanessa Ginet et al.
The American journal of pathology, 175(5), 1962-1974 (2009-10-10)
The multiplicity of cell death mechanisms induced by neonatal hypoxia-ischemia makes neuroprotective treatment against neonatal asphyxia more difficult to achieve. Whereas the roles of apoptosis and necrosis in such conditions have been studied intensively, the implication of autophagic cell death
Nandhakumar Thayanidhi et al.
Molecular biology of the cell, 21(11), 1850-1863 (2010-04-16)
Toxicity of human alpha-synuclein when expressed in simple organisms can be suppressed by overexpression of endoplasmic reticulum (ER)-to-Golgi transport machinery, suggesting that inhibition of constitutive secretion represents a fundamental cause of the toxicity. Whether similar inhibition in mammals represents a
Raymond E Hulse et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 28(47), 12199-12211 (2008-11-21)
In brain, monomeric immunoglobin G (IgG) is regarded as quiescent and only poised to initiate potentially injurious inflammatory reactions via immune complex formation associated with phagocytosis and tumor necrosis factor alpha (TNF-alpha) production in response to disease. Using rat hippocampal
Articles
Autophagy is a regulated process involved in cell growth, development, and recycling of cytoplasmic components in cells.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service