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Sigma-Aldrich

Dipeptidylpeptidase IV Inhibitor I

The Dipeptidylpeptidase IV Inhibitor I controls the biological activity of Dipeptidylpeptidase IV. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

Synonym(s):

Dipeptidylpeptidase IV Inhibitor I, Diprotin A

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About This Item

Empirical Formula (Hill Notation):
C17H31N3O4
Molecular Weight:
341.45
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

Assay

≥95% (HPLC)

form

amorphous solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated (hygroscopic)

color

white

solubility

water: 1 mg/mL
DMSO: 5 mg/mL

shipped in

ambient

storage temp.

2-8°C

General description

A dipeptidylpeptidase IV (DPP IV) inhibitor that inhibits both endo- and exopeptidase activities of DPPIV.
A dipeptidylpeptidase IV (DPP IV) inhibitor.

Biochem/physiol Actions

Cell permeable: no
Primary Target
dipeptidylpeptidase IV (DPP IV)
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Standard Handling (A)

Sequence

Ile-Pro-Ile

Reconstitution

Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 6 months at 4°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 3


Certificates of Analysis (COA)

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Hyunyee Yoon et al.
Biomolecules & therapeutics, 29(2), 154-165 (2020-11-06)
This study aimed to investigate whether the antidiabetic drugs dipeptidyl peptidase 4 (DPP4) inhibitors such as evogliptin and sitagliptin affect the membrane DPP4 (mDPP4) enzymatic activity and immune function of T helper1 (Th1) cells in terms of cytokine expression and

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