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Sigma-Aldrich

2-Guanidinoethylmercaptosuccinic Acid

Potent inhibitor of a carboxypeptidase B-like processing enzyme referred to as enkephalin convertase (Ki = 8.8 nM).

Synonym(s):

2-Guanidinoethylmercaptosuccinic Acid, GEMSA

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About This Item

CAS Number:
UNSPSC Code:
12352106
NACRES:
NA.77

Quality Level

Assay

≥99% (TLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated (hygroscopic)

color

white

solubility

water: soluble

shipped in

ambient

storage temp.

2-8°C

InChI

1S/C7H13N3O4S/c8-7(9)10-1-2-15-4(6(13)14)3-5(11)12/h4H,1-3H2,(H,11,12)(H,13,14)(H4,8,9,10)

InChI key

VKVCLXDFOQQABP-UHFFFAOYSA-N

General description

Potent inhibitor of a carboxypeptidase B-like processing enzyme referred to as enkephalin convertase (Ki = 8.8 nM). Ideal for use in affinity chromatography of the enzyme.
Potent inhibitor of carboxypeptidase B-like processing enzyme referred to as enkephalin convertase (Ki = 8.8 nM). Ideal for use in affinity chromatography of the enzyme.

Biochem/physiol Actions

Cell permeable: no
Primary Target
Enkephalin convertase
Product does not compete with ATP.
Reversible: no
Target Ki: 8.8 nM for enkephalin convertase

Warning

Toxicity: Standard Handling (A)

Other Notes

Bommer, M., et al. 1989. Brain Res. 492, 305.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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