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362225

Sigma-Aldrich

β₂-Glycoprotein 1, Human Plasma

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Synonym(s):
Apolipoprotein H
UNSPSC Code:
12352202
NACRES:
NA.25

Assay

≥95% (SDS-PAGE)

Quality Level

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

concentration

≥2 PEU/mg solid (antigen content)

shipped in

ambient

storage temp.

2-8°C

Related Categories

General description

Native β2-glycoprotein 1 from human plasma. A carbohydrate-rich plasma protein that is a constituent of several lipoprotein particles. Possesses sialylated and galactosylated bi- and triantennary oligosaccharides.

Warning

Toxicity: Standard Handling (A)

Unit Definition

One PEU is defined as the amount of β₂-glycoprotein 1 present in 1 ml of normal plasma (~200 µg).

Physical form

Lyophilized from 200 mM glycine, 150 mM NaCl, pH 7.5.

Preparation Note

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for 1 month at 4°C or for up to 4 h at 20°C.
Reconstitute with 1 ml of distilled H₂O.

Other Notes

Wang, S.X., et al. 1999. Biochemistry 38, 9477.
Cassader, M., et al. 1994. Artherosclerosis 110, 45.
Walsh, M.T., et al. 1990. Biochem. 29, 6250.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Chronic hepatitis B virus (HBV) infection remains one of the leading causes of hepatocellular carcinoma (HCC) globally. However, the mechanism underlying the mediation by HBV surface proteins (HBsAgs) of the early steps in the virus life cycle and following HCC development

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