345250
N-Acetyllactosamine
A substrate for galactosidases, fucosyltransferases, and sialyltransferases. Useful as a lectin inhibitory sugar.
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Synonym(s):
N-Acetyllactosamine, O-β-D-Galactopyranosyl-β1,4-2-acetamido-2-deoxy-D-glucose, Galβ1,4GlcNAc, LacNAc
Empirical Formula (Hill Notation):
C14H25NO11
Recommended Products
Quality Level
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
white to off-white
solubility
water: 5 mg/mL
shipped in
ambient
storage temp.
2-8°C
InChI
1S/C14H25NO11/c1-4(18)15-7-9(20)12(6(3-17)24-13(7)23)26-14-11(22)10(21)8(19)5(2-16)25-14/h5-14,16-17,19-23H,2-3H2,1H3,(H,15,18)/t5-,6-,7-,8+,9-,10+,11-,12-,13-,14+/m1/s1
InChI key
KFEUJDWYNGMDBV-LODBTCKLSA-N
General description
A substrate for galactosidases, fucosyltransferases, and sialyltransferases. Useful as a lectin inhibitory sugar.
Application
- Mass Spectrometry Analysis of Glycopeptides Enriched by Anion Exchange-Mediated Methods Reveals PolyLacNAc-Extended N-Glycans in Integrins and Tetraspanins in Melanoma Cells.: This research demonstrates the application of mass spectrometry in identifying N-acetyllactosamine extensions on glycoproteins in melanoma cells, providing insights into cellular adhesion and signaling mechanisms (Čaval et al., 2024).
Warning
Toxicity: Standard Handling (A)
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Analysis Note
Single spot by TLC
Other Notes
Gunnarsson, A., et al. 1984. Infect. Immun.45, 41.
Loomes, L.M., et al. 1984. Nature307, 560.
Loomes, L.M., et al. 1984. Nature307, 560.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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