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324900

Sigma-Aldrich

L-(–)-Epinephrine-(+)-bitartrate

α,β-Adrenergic receptor agonist.

Synonym(s):

L-(–)-Epinephrine-(+)-bitartrate, 1-(3,4-Dihydroxyphenyl)-2-(methylamino)ethanol, Adrenaline Bitartrate

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About This Item

Empirical Formula (Hill Notation):
C9H13NO3 · xC4H6O6
CAS Number:
51-42-3
Molecular Weight:
183.20 (free base basis)
MDL number:
MFCD00035077
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

100

Assay

≥95% (TLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated (hygroscopic)

color

white

solubility

ethanol: soluble
water: soluble

shipped in

ambient

storage temp.

2-8°C

InChI

1S/C9H13NO3.C4H6O6/c1-10-5-9(13)6-2-3-7(11)8(12)4-6;5-1(3(7)8)2(6)4(9)10/h2-4,9-13H,5H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t9-;1-,2-/m01/s1

InChI key

YLXIPWWIOISBDD-NDAAPVSOSA-N

General description

α,β-Adrenergic receptor agonist. Has positive chronotropic and inotropic effects on heart muscle. Activates adenylate cyclase to generate cAMP from ATP.
An α,β-adrenergic receptor agonist. Has positive chronotropic and inotropic effects on cardiac muscle. Its major actions are mediated via activation of adenylate cyclase. Enhances mitochondrial oxidation of substrates.

Biochem/physiol Actions

Cell permeable: no
Primary Target
α,β-Adrenergic receptor agonist
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Highly Toxic & Carcinogenic / Teratogenic (I)

Reconstitution

Unstable in solution; reconstitute just prior to use.

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Oudit, G.Y., and Butler, D.G. 1995. Am. J. Physiol.268, R1273.
Mohan, C., et al. 1991. Arch. Biochem. Biophys.287, 18.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H300

Hazard Classifications

Acute Tox. 1 Oral

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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