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Merck
CN

252805

DHEA

≥97% (HPLC), powder, GABAA receptor negative modulator, Calbiochem®

Synonym(s):

DHEA, Dehydro- epi-androsterone, Dehydroisoandrosterone, Prasterone, 3-Hydroxyandrost-5-en-17-one

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About This Item

Empirical Formula (Hill Notation):
C19H28O2
CAS Number:
Molecular Weight:
288.42
UNSPSC Code:
12352211
NACRES:
NA.77
MDL number:
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Product Name

DHEA, Major secretory steroidal product of the adrenal gland.

SMILES string

O[C@H]1CC[C@@]2([C@@H]3[C@H]([C@H]4[C@](CC3)(C(=O)CC4)C)CC=C2C1)C

InChI

1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h3,13-16,20H,4-11H2,1-2H3/t13-,14-,15-,16-,18-,19-/m0/s1

InChI key

FMGSKLZLMKYGDP-USOAJAOKSA-N

description

Merck USA index - 14, 2871

assay

≥97% (HPLC)

form

powder

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

off-white

solubility

ethanol: 20 mg/mL

shipped in

ambient

storage temp.

10-30°C

Quality Level

Related Categories

Biochem/physiol Actions

Cell permeable: no
Primary Target
Negative modulators of GABAA receptors
Product does not compete with ATP.
Reversible: no

Disclaimer

Toxicity: Standard Handling (A)

General description

Major secretory steroidal product of the adrenal gland. DHEA and its sulfated metabolite, DHEA-S, are negative modulators of GABAA receptors.

Other Notes

Hansen, S.L., et al. 1999. Mol. Pharmacol. 55, 489.
Imamura, M., and Prasad, C. 1998. Biochem. Biophys. Res. Commun.243, 771.
Majewska, M.D., et al. 1990. Brain Res.526, 143.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazard

signalword

Warning

hcodes

Hazard Classifications

Repr. 2

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

涉药品监管产品
This item has

Certificates of Analysis (COA)

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