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Sigma-Aldrich

Cytochalasin B, Dihydro-

Induces changes in cell morphology and motility with no effect on sugar transport.

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Synonym(s):
Cytochalasin B, Dihydro-
Empirical Formula (Hill Notation):
C29H39NO5
CAS Number:
39156-67-7
Molecular Weight:
481.62
MDL number:
MFCD12910542
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

100

Assay

≥98% (TLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

white

solubility

methanol: 10 mg/mL
ethanol: 2 mg/mL
DMSO: 5 mg/mL

shipped in

ambient

storage temp.

−20°C

InChI

1S/C29H39NO5/c1-18-9-7-13-22(31)15-16-25(32)35-29-23(14-8-10-18)27(33)20(3)19(2)26(29)24(30-28(29)34)17-21-11-5-4-6-12-21/h4-6,8,11-12,14,18-19,22-24,26-27,31,33H,3,7,9-10,13,15-17H2,1-2H3,(H,30,34)/b14-8+/t18-,19-,22-,23+,24+,26+,27-,29-/m1/s1

InChI key

WIULKAASLBZREV-RXPQEOCGSA-N

General description

Induces changes in cell morphology and motility with no effect on sugar transport. Used as a specific marker in studies of high affinity cytochalasin binding sites unrelated to sugar transport. Disrupts the equilibrium between monomeric and polymeric actin.
Induces changes in cell morphology and motility with no effect on sugar transport. Used as specific marker in studies of high affinity cytochalasin binding sites unrelated to sugar transport. Disrupts the equilibrium between monomeric and polymeric actin.

Biochem/physiol Actions

Cell permeable: no
Primary Target
Changes in cell morphology and motility
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Highly Toxic & Carcinogenic / Teratogenic (I)

Reconstitution

Following reconstitution refrigerate (4°C). Stock solutions are stable for up to 6 months at 4°C.

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Lin, D.C., and Lin, S. 1978. J. Biol. Chem.253, 1415.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Statements

H300 + H310 + H330,H351

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Carc. 2

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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