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Merck
CN

238470

Cremophor® EL

Synonym(s):

Castor oil polyoxyethylene ether, Ethoxylated castor oil, PEG-35 castor oil, Polyoxyl 35 castor oil, polyoxyl 35 castor oil

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About This Item

CAS Number:
61791-12-6
UNSPSC Code:
12162002
NACRES:
NA.21
MDL number:
MFCD00130879

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SMILES string

ClCC(OC(=O)N)CCl

InChI

1S/C4H7Cl2NO2/c5-1-3(2-6)9-4(7)8/h3H,1-2H2,(H2,7,8)

InChI key

JMNCUXPHXKHBPY-UHFFFAOYSA-N

form

liquid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

clear pale yellow

CMC

~0.02%

solubility

ethanol: soluble
water: soluble, clear (at higher temperatures the solution will be come turbid)

density

1,050 g/cm3

application(s)

(Excipient in drug)

shipped in

ambient

storage temp.

2-8°C

Quality Level

100

Related Categories

Application


  • Proteomic responses of carotenoid and retinol administration to Mongolian gerbils.: This research examines the proteomic responses in Mongolian gerbils administered with carotenoids and retinol. Cremophor® EL is utilized as a solubilizing agent for these compounds, highlighting its role in biochemical studies involving lipid-soluble substances (Bohn et al., 2018).

Disclaimer

Toxicity: Standard Handling (A)

General description

1 Set = 5 X 25 GM
A mixture of polyoxyethylated triglycerides, by reacting castor oil with ethylene oxide in a molar ratio of 1 : 35, that acts as a nonionic surfactant and serves as a formulation vehicle (p.o. and i.v. administration) for poorly-water soluble pharmacological agents.
Hydrophilic-lipophilic balance (HLB) ~ 12 - 14.

Other Notes

Gelderblom, H., et al. 2001. Eur. J. Cancer37, 1590.

Sparreboom, A., et al. 1996. Cancer Res.56, 2112.
Woodcock, D.M., et al. 1990. Cancer Res.50, 4199.

Packaging

Packaged under inert gas

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Cremophor is a registered trademark of BASF SE

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

494.6 °F - Not applicable

flash_point_c

257 °C - Not applicable

Certificates of Analysis (COA)

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