Coagulation Factor XI, Human Plasma

Coagulation Factor XI, Human Plasma, CAS 9013-55-2, is a native coagulation factor XI with two identical polypeptide chains linked by disulfide bond. It is activated to Factor XIa by Factor XIIa.

Native coagulation factor XI from human plasma. Consists of two identical polypeptide chains linked by disulfide bonds, that yield a single band at 80 kDa upon reduction with β-mercaptoethanol. In vivo, Factor XI is activated to Factor XIa by Factor XIIa.

Native coagulation factor XI from human plasma. Consists of two identical polypeptide chains linked by disulfide bonds, that yield a single band at 80,000 on reduction with β-mercaptoethanol. In vivo, Factor XI is activated to Factor XIa by Factor XIIa.

Please refer to vial label for lot-specific concentration.

Toxicity: Standard Handling (A)

In 150 mM NaCl, 4 mM sodium acetate buffer, pH 5.3.

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Following initial thaw, aliquot and freeze (-70°C).

Clotting activity is determined by comparison to a standard curve produced using normal pooled human plasma

single band by SDS-PAGE

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