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Millipore

CHAPSO

Unique detergent with high CMC that solubilizes membrane-bound proteins in their native state.

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Synonym(s):
CHAPSO, 3-[(3-Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate
Empirical Formula (Hill Notation):
C32H58N2O8S
CAS Number:
82473-24-3
Molecular Weight:
630.88
MDL number:
MFCD00081079
UNSPSC Code:
12352200
NACRES:
NA.25

Quality Level

100

Assay

>98% (TLC)

form

solid

mol wt

micellar wt 9960

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

aggregation number

11

color

white

CMC

8 mM

solubility

water: soluble

shipped in

ambient

storage temp.

2-8°C

InChI

1S/C32H58N2O8S/c1-20(7-10-29(39)33-13-6-14-34(4,5)18-23(36)19-43(40,41)42)24-8-9-25-30-26(17-28(38)32(24,25)3)31(2)12-11-22(35)15-21(31)16-27(30)37/h20-28,30,35-38H,6-19H2,1-5H3,(H-,33,39,40,41,42)/t20-,21+,22-,23?,24-,25+,26+,27-,28+,30+,31+,32-/m1/s1

InChI key

GUQQBLRVXOUDTN-XOHPMCGNSA-N

General description

Unique detergent with high CMC that solubilizes membrane-bound proteins in their native state (aggregation number: 11; CMC: 8 mM; micellar weight: 9960). Capable of solubilizing the opiate receptor to a state exhibiting reversible binding of opiates. Has a higher solubility than CHAPS because of its more polar head group.
Unique detergent with high CMC that solubilizes membrane-bound proteins in their native state. Capable of solubilizing opiate receptor to a state exhibiting reversible binding of opiates. Has higher solubility than CHAPS because of its more polar head group. Aggregation number: 11.

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 3 days at 4°C.

Other Notes

Simonds, W.F., et al. 1980. Proc. Natl. Acad. Sci. USA77, 4623.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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