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218763

Sigma-Aldrich

Caspase-6 Substrate III, Fluorogenic

A fluorogenic substrate for caspase-6 (Mch2).

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Synonym(s):
Caspase-6 Substrate III, Fluorogenic, Z-VEID-AFC
Empirical Formula (Hill Notation):
C38H44F3N5O12
CAS Number:
Molecular Weight:
819.78
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

Assay

≥95% (HPLC)

form

lyophilized

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated
protect from light

solubility

DMSO: 5 mg/mL

fluorescence

λex ~400 nm
λem ~505 nm

shipped in

ambient

storage temp.

−20°C

General description

A fluorogenic substrate for caspase-6 (Mch2). Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore (excitation maximum: ~400 nm; emission maximum: ~505 nm).
A fluorogenic substrate for caspase-6 (Mch2). Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore.

Biochem/physiol Actions

Cell permeable: no
Primary Target
A fluorogenic substrate for caspase-6 (Mch2
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Standard Handling (A)

Sequence

Z-Val-Glu-Ile-Asp-AFC

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Hazard Statements

Precautionary Statements

Hazard Classifications

Aquatic Chronic 4

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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