218745
Caspase Inhibitor III
The Caspase Inhibitor III, also referenced under CAS 634911-80-1, controls the biological activity of Caspase. This small molecule/inhibitor is primarily used for Cancer applications.
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Synonym(s):
Caspase Inhibitor III, Boc-D-FMK
Empirical Formula (Hill Notation):
C11H18FNO5
Recommended Products
Quality Level
form
semisolid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
desiccated
color
off-white
solubility
DMSO: 5 mg/mL
shipped in
ambient
storage temp.
−20°C
InChI
1S/C11H18FNO5/c1-11(2,3)18-10(16)13-7(8(14)6-12)5-9(15)17-4/h7H,5-6H2,1-4H3,(H,13,16)
InChI key
MXOOUCRHWJYCAL-UHFFFAOYSA-N
General description
A broad-spectrum cell-permeable and irreversible caspase inhibitor.
A cell-permeable, irreversible, broad-spectrum caspase inhibitor.
Biochem/physiol Actions
Cell permeable: yes
Primary Target
broad spectrum caspase
broad spectrum caspase
Product does not compete with ATP.
Reversible: no
Warning
Toxicity: Standard Handling (A)
Sequence
Boc-Asp(OMe)-CH₂F*
Reconstitution
Following reconstitution aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 4 months at 4°C or for up to 1 year at -20°C.
Analysis Note
single spot by TLC
Other Notes
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
D’Mello, S.R., et al. 1998. J. Neurochem. 70, 1809.
D’Mello, S.R., et al. 1998. J. Neurochem. 70, 1809.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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