208698-M
Calmodulin, Human Brain
Calmodulin, Human Brain, is a ubiquitous Ca2+-binding protein that serves as a physiological effector of a wide range of biological processes. Purified from human brain.
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Synonym(s):
CaM, Ca 2+/Calmodulin, CaM, Ca2+/Calmodulin
UNSPSC Code:
12352202
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Quality Level
Assay
≥95% (native PAGE)
form
lyophilized
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
storage temp.
−20°C
General description
Calmodulin purifed from human brain.
Calmodulin purifed from human brain. Calmodulin is a ubiquitous Ca2+-binding protein distributed in eukaryotic cells that serves as a major physiological effector for a wide range of cellular responses. The Ca2+-calmodulin complex is involved in the maintenance of intracellular Ca2+ homeostasis, as well as in the regulation of the intracellular concentration of other second messengers, such as cyclic AMP and inositol trisphosphate.
Warning
Toxicity: Standard Handling (A)
Unit Definition
One unit is defined as the amount of calmodulin that will give rise to 50% of the maximal enzyme activation of a standard level of activator-deficient 3ʹ,5ʹ-cyclic nucleotide phosphodiesterase.
Physical form
Lyophilized from protein solution with 2 mM EDTA.
Reconstitution
Reconstitute with distilled water. H₂O (1 mg/ml)
Other Notes
O′Neil, K.T., and DeGrado, W.F. 1990. Trends Pharmacol. Sci.15, 59.
Gopalakrishna, R., and Anderson, W.B. 1982. Biochem. Biophys. Res. Commun.104, 830.
Sharma, R.K., and Wang, J.H. 1979. Adv. Cyclic Nucleotide Res.10, 187.
Gopalakrishna, R., and Anderson, W.B. 1982. Biochem. Biophys. Res. Commun.104, 830.
Sharma, R.K., and Wang, J.H. 1979. Adv. Cyclic Nucleotide Res.10, 187.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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