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Merck
CN

203806

5-Bromo-2′-deoxyuridine

Thymidine analog. Useful for the study of DNA synthesis where it is incorporated into DNA in place of thymidine.

Synonym(s):

5-Bromo-2′-deoxyuridine, 5-BrdU

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About This Item

CAS Number:
59-14-3
UNSPSC Code:
12352208
NACRES:
NA.51
MDL number:
MFCD00006529

Key Documents

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Product Name

5-Bromo-2′-deoxyuridine, Thymidine analog. Useful for the study of DNA synthesis where it is incorporated into DNA in place of thymidine.

SMILES string

Brc1[c]([nH][c]([n](c1)C2OC(C(C2)O)CO)=O)=O

InChI

1S/C9H11BrN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)

InChI key

WOVKYSAHUYNSMH-UHFFFAOYSA-N

description

RTECS - YU7350000

assay

≥98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white

solubility

water: 10 mg/mL
0.1 M NaOH: 50 mg/mL
DMSO: 50 mg/mL

shipped in

ambient

storage temp.

15-25°C

Quality Level

100

Related Categories

Disclaimer

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

General description

Thymidine analog. Used for the study of DNA synthesis where it is incorporated into DNA in place of thymidine. Can be used both in vitro and in vivo to label DNA. The resulting DNA can be used in conjuction with BrdU (Ab-2) Monoclonal Antibody (Cat. No. NA20) or BrdU Immunohistochemical System (Cat. No. HCS24) for the immunohistochemical analysis of cell proliferation.
Thymidine analog. Useful for the study of DNA synthesis where it is incorporated into DNA in place of thymidine. Can be used both in vitro and in vivo to label DNA. The resulting DNA can be used in conjunction with BrdU (Ab-2) Monoclonal Antibody (Cat. No. NA20 ) for the immunohistochemical analysis of cell proliferation.

Other Notes

Garabedian, E.M., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 15382.
Cattoretti, G., et al. 1993. J. Pathol. 171, 83.
Fukuda, K., et al. 1990. Anal. Quant. Cytol. Histol. 12, 135.

Preparation Note

Following reconstitution, sterilize by filtration through a 0.22 µm filter, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazard
GHS08

signalword

Danger

Hazard Classifications

Muta. 1B - Repr. 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

Certificates of Analysis (COA)

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