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Sigma-Aldrich

PKA\PKC Inhibitor Cocktail

The PKA\PKC Inhibitor Cocktail controls the biological activity of PKA\PKC. This small molecule/inhibitor is primarily used for Biochemicals applications.

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UNSPSC Code:
12352200
eCl@ss:
32160405
NACRES:
NA.41

manufacturer/tradename

Upstate®

technique(s)

activity assay: suitable (kinase)

NCBI accession no.

NM_002730.3
NM_207518.1

UniProt accession no.

P17612

shipped in

wet ice

Application

Inhibitor cocktail for use in kinase assays.

Biochem/physiol Actions

Inhibitor Type: Kinase
Protein Target: PKA C-alpha

Quality

Routinely evaluated in a kinase assay.

Physical form

20mM MOPS, pH 7.2, 25mM β-glycerol phosphate, 1mM CaCl2, 1mM sodium orthovanadate, 1mM dithiothreitol

Storage and Stability

1 year at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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J S Godde et al.
Nucleic acids research, 23(22), 4557-4564 (1995-11-25)
We establish that the TATA binding protein (TBP) in the presence of TFIIA recognizes the TATA box in nucleosomal DNA dependent on the dissociation of the amino-terminal tails of the core histones from the nucleosome and the position of the
C/EBPbeta, but not C/EBPalpha, is essential for ductal morphogenesis, lobuloalveolar proliferation, and functional differentiation in the mouse mammary gland.
T N Seagroves,S Krnacik,B Raught,J Gay,B Burgess-Beusse,G J Darlington,J M Rosen
Genes & Development null
Conversion of stereoisomers of leukotriene B4 to dihydro and tetrahydro metabolites by porcine leukocytes.
W S Powell,F Gravelle
Biochimica et Biophysica Acta null

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