182750
ASB-14
A zwitterionic amidosulfobetaine detergent useful for solubilizing proteins visualized by 2D-electrophoresis.
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Synonym(s):
ASB-14
Empirical Formula (Hill Notation):
C22H46N2O4S
Molecular Weight:
434.68
UNSPSC Code:
12161902
NACRES:
NA.21
Recommended Products
Quality Level
Assay
≥97% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
desiccated (hygroscopic)
color
white to off-white
solubility
water: 50 mg/mL
shipped in
ambient
storage temp.
10-30°C
Related Categories
General description
A zwitterionic amidosulfobetaine detergent that exhibits better protein extraction properties than CHAPS.
A zwitterionic amidosulfobetaine detergent useful for solubilizing proteins visualized by 2D-electrophoresis. The increased solubilization produced by this detergent enables the identification of previously undetected membrane proteins.
Application
- Effect of bovine pericardial extracellular matrix scaffold niche on seeded human mesenchymal stem cell function.: This paper explores the influence of the bovine pericardial extracellular matrix on human mesenchymal stem cells, with ASB-14 used to modulate cellular responses. The research contributes to advancements in scaffold-based tissue engineering (Liu et al., 2016).
- In vivo xenogeneic scaffold fate is determined by residual antigenicity and extracellular matrix preservation.: Investigating the fate of xenogeneic scaffolds in vivo, this study shows that ASB-14 helps maintain extracellular matrix integrity and reduce antigenicity, which is critical for successful scaffold integration and function in tissue engineering (Wong et al., 2016).
Warning
Toxicity: Irritant (B)
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 year at -20°C.
Other Notes
Carroll, J., et al. J. Biol. Chem.277, 50311.
Herbert, B. 1999. Electrophoresis20, 660.
Chevallet, M. et al. 1998. Electrophoresis 19, 1901.
Herbert, B. 1999. Electrophoresis20, 660.
Chevallet, M. et al. 1998. Electrophoresis 19, 1901.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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