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165300

Sigma-Aldrich

L-(+)-2-Amino-4-phosphonobutyric Acid

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Synonym(s):
L-(+)-2-Amino-4-phosphonobutyric Acid, L-AP4
Empirical Formula (Hill Notation):
C4H10NO5P
CAS Number:
Molecular Weight:
183.10
MDL number:
UNSPSC Code:
12352200

Assay

≥98% (HPLC)

Quality Level

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white

solubility

dilute aqueous base: 5 mg/mL

shipped in

ambient

storage temp.

2-8°C

InChI

1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10)/p-2/t3-/m0/s1

InChI key

DDOQBQRIEWHWBT-VKHMYHEASA-L

General description

Phosphonic acid analog of L-glutamic acid. A selective group III metabotropic glutamate receptor agonist. Also a potent, pathway-specific synaptic depressant.

Warning

Toxicity: Irritant (B)

Other Notes

Pin, J.-P., and Duvoisin, R. 1995. Neuropharmacology 34, 1.
Saugstad, J.A., et al. 1995. Mol. Pharmacol. 45, 367.
Tones, M.A., et al. 1995. NeuroReport 7, 117.
Schoepp, D.D. 1994. Neurochem. Int. 24, 439.
Nakanishi, S. 1992. Science 258, 597.
Tanabe, Y., et al. 1992. Neuron 8, 169.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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