16-155
Anti-phospho-Ser/Thr-Pro MPM-2 Antibody, FITC conjugate
Upstate®, from mouse
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UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
mouse
Quality Level
conjugate
FITC conjugate
antibody form
purified antibody
antibody product type
primary antibodies
clone
monoclonal
species reactivity (predicted by homology)
all
manufacturer/tradename
Upstate®
technique(s)
immunocytochemistry: suitable
shipped in
wet ice
target post-translational modification
phosphorylation (pSer/pThr)
General description
This antibody recognizes a variety of proteins that are phosphorylated during mitosis.
Anti-phospho-Ser/Thr-Pro, MPM-2 (05-368) conjugated to fluorescein-5-EX, succinimidyl ester (FSE)
Anti-phospho-Ser/Thr-Pro, MPM-2 (05-368) conjugated to fluorescein-5-EX, succinimidyl ester (FSE)
Application
Detect phospho-Ser/Thr-Pro also known as Mitotic protein #2 with Anti-phospho-Ser/Thr-Pro Antibody, MPM-2, FITC conjugate (Mouse Monoclonal Antibody), that has been demonstrated to work in ICC.
For applications in which an FITC conjugate is advantageous, such as ICC.
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Cell Cycle, DNA Replication & Repair
Cell Cycle, DNA Replication & Repair
Quality
routinely evaluated in immunocytochemistry on A431 mitotic cells fixed with 3.7% paraformaldehyde
Physical form
TBS, pH 8.0, 0.05% sodium azide and 30% glycerol
Storage and Stability
Stable for 1 year at -20°C from date of shipment. Store in the dark. For maximum recovery of product, centrifuge the vial.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 2
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Comparable stabilisation, structural changes and activities can be induced in FGF by a variety of HS and non-GAG analogues: implications for sequence-activity relationships.
Timothy R Rudd,Katarzyna A Uniewicz,Alessandro Ori,Scott E Guimond,Mark A Skidmore et al.
Organic & Biomolecular Chemistry null
William Clay Gustafson et al.
Cancer cell, 26(3), 414-427 (2014-09-02)
MYC proteins are major drivers of cancer yet are considered undruggable because their DNA binding domains are composed of two extended alpha helices with no apparent surfaces for small-molecule binding. Proteolytic degradation of MYCN protein is regulated in part by
cdc25 is one of the MPM-2 antigens involved in the activation of maturation-promoting factor.
Kuang, J, et al.
Molecular Biology of the Cell, 5, 135-145 (1994)
Sequence-specific and phosphorylation-dependent proline isomerization: a potential mitotic regulatory mechanism.
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Science (New York, N.Y.), 278, 1957-1960 (1997)
A small-molecule inhibitor targeting the mitotic spindle checkpoint impairs the growth of uterine leiomyosarcoma.
Shan, W; Akinfenwa, PY; Savannah, KB; Kolomeyevskaya, N; Laucirica, R; Thomas, DG; Odunsi et al.
Clinical cancer research : an official journal of the American Association for Cancer Research null
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