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1.47345

SAFC

Sodium dihydrogen phosphate dihydrate

new

granulated, USP, Ph. Eur., EMPROVE® EXPERT, JPE, BP, ChP

Pharma Manufacturing

Synonym(s):

Sodium phosphate monobasic dihydrate, Sodium dihydrogen phosphate dihydrate

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About This Item

Linear Formula:
NaH2PO4 · 2H2O
CAS Number:
13472-35-0
Molecular Weight:
156.01
MDL number:
MFCD00149209

Agency

BP
ChP
JPE
Ph. Eur.
USP

Quality Level

500

product line

EMPROVE® EXPERT

form

granular

impurities

low in endotoxins

application(s)

liquid formulation
parenterals
pharma/biopharma processes

storage temp.

15-25°C

SMILES string

O.O.[Na+].OP(O)([O-])=O

InChI

1S/Na.H3O4P.2H2O/c;1-5(2,3)4;;/h;(H3,1,2,3,4);2*1H2/q+1;;;/p-1

InChI key

VBJGJHBYWREJQD-UHFFFAOYSA-M

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General description

Standard bulk materials often show a tendency for caking, clumping and dust formation which results in laborious weighing and manual de-caking processes with a negative impact on manufacturing efficiency. Due to its granulated form, Sodium dihydrogen phosphate dihydrate granulated is free-flowing and easy to handle. Its greatly reduced caking behavior facilitates processability, speeds up manufacturing processes and increases operator safety. As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Sodium dihydrogen phosphate dihydrate is used as a buffer component for Biomolecule downstream processing steps and final formulation as well as small molecule final formulation.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Regulatory Information

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Articles

Facilitate Handling of Bulk Powders with Dry Granulation

Handling bulk powders at a large scale in the pharmaceutical, biopharmaceutical, and bioprocessing setting is challenging. Compared to powders, granulated materials experience far less caking, have better flowability, and are easier to handle, even after long-term storage.

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