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Key Documents

14-477-M

Sigma-Aldrich

Cdk5/p35 Protein, active, 10 µg

Active complex of recombinant full length human Cdk5 containing & N-terminal His6-tag & recombinant full-length human p35 containing an N-terminal GST-tag, for use in Kinase Assays.

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100 MG
CN¥1,241.24

CN¥1,241.24

Available to ship onApril 23, 2025Details

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100 MG
CN¥1,241.24

About This Item

UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.26

CN¥1,241.24

Available to ship onApril 23, 2025Details

Sign In for Best Price
Request a Bulk Order

biological source

human

Quality Level

100

recombinant

expressed in baculovirus infected Sf21 cells

mol wt

Mw 34 kDa (cdk5)
Mw 61 kDa (p35 with GST-tag)

manufacturer/tradename

Upstate®

technique(s)

activity assay: suitable (kinase)

NCBI accession no.

NM_004935.2

UniProt accession no.

Q00535

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This Item
BX0220319953154628
Benzene Pharmaceutical Secondary Standard; Certified Reference Material

PHR1310

Benzene

Benzene Meets ACS Specifications, Meets Reagent Specifications for testing USP/NF monographs GR ACS

BX0220

Benzene

Benzene ACS reagent, ≥99.0%

319953

Benzene

Benzene ACS spectrophotometric grade, ≥99%

154628

Benzene

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

-

application(s)

-

format

neat

format

-

format

-

format

-

Quality Level

300

Quality Level

200

Quality Level

200

Quality Level

200

grade

certified reference material, pharmaceutical secondary standard

grade

-

grade

ACS reagent

grade

ACS spectrophotometric grade

storage temp.

2-30°C

storage temp.

room temp

storage temp.

-

storage temp.

-

General description

Complex of recombinant fulllength human cdk5 containing and N-terminal His6-tag and recombinant full-length human p35 containing an N-terminal GST-tag
Product Source: Both are expressed by baculovirus in Sf21 insect cells

Biochem/physiol Actions

Protein Target: CDK5/p35
Target Sub-Family: CMGC

Packaging

Also available in 250μg size as catalog # 14-477M - Call for pricing and availability.

Quality

routinely evaluated by phosphorylation of Histone H1

Physical form

Ni-NTA agarose

Storage and Stability

1 year at -70°C

Other Notes

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
  • Specification Sheet

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    Ward G Walkup et al.
    The Journal of biological chemistry, 290(8), 4908-4927 (2014-12-24)
    synGAP is a neuron-specific Ras and Rap GTPase-activating protein (GAP) found in high concentrations in the postsynaptic density (PSD) fraction from the mammalian forebrain. We have previously shown that, in situ in the PSD fraction or in recombinant form in
    Ward G Walkup et al.
    eLife, 5 (2016-10-21)
    SynGAP is a Ras/Rap GTPase-activating protein (GAP) that is a major constituent of postsynaptic densities (PSDs) from mammalian forebrain. Its α1 isoform binds to all three PDZ (PSD-95, Discs-large, ZO-1) domains of PSD-95, the principal PSD scaffold, and can occupy

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