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Sigma-Aldrich

FKHR Protein, 100 µg

N-terminal, Glutathione-Stransferase (GST) tagged, full-length fusion protein corresponding to human FKHR.

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About This Item

UNSPSC Code:
12352200
eCl@ss:
32160405
NACRES:
NA.32

biological source

human

mol wt

Mw 105 kDa

manufacturer/tradename

Upstate®

technique(s)

activity assay: suitable (kinase)
western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

Gene Information

human ... FOXO1(2308)

General description

Product Source: Recombinant human expressed in E. coli

Application

N-terminal, Glutathione-Stransferase (GST) tagged, full-length fusion protein corresponding to human FKHR.

Quality

routinely evaluated by phosphorylation by Akt1

Physical form

Glutathione-agarose

Storage and Stability

1 year at -70°C

Other Notes

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Skin Sens. 1

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Arthur Bikbaev et al.
Scientific reports, 5, 14527-14527 (2015-09-30)
The formation and maintenance of connectivity are critically important for the processing and storage of information in neuronal networks. The brain extracellular matrix (ECM) appears during postnatal development and surrounds most neurons in the adult mammalian brain. Importantly, the removal
Stefan Weigel et al.
Journal of neurophysiology, 107(2), 640-648 (2011-10-28)
The midbrain is an important processing area for sensory information in vertebrates. The optic tectum and its mammalian counterpart, the superior colliculus, receive multimodal, topographic information and contain a sensory map that plays a role in spatial attention and orientation
Andrew J Weitz et al.
Neuron, 104(6), 1153-1167 (2019-11-02)
Anatomical and behavioral data suggest that the ventrolateral orbitofrontal cortex (VLO), which exhibits extensive connectivity and supports diverse sensory and cognitive processes, may exert global influence over brain activity. However, this hypothesis has never been tested directly. We applied optogenetic
Rashmi N Kumar et al.
Molecular and cellular biology, 26(1), 50-62 (2005-12-16)
The GTPase-deficient, activated mutant of Galpha12 (Galpha12Q229L, or Galpha12QL) induces neoplastic growth and oncogenic transformation of NIH 3T3 cells. Using microarray analysis, we have previously identified a role for platelet-derived growth factor receptor alpha (PDGFRalpha) in Galpha12-mediated cell growth (R.
Gaurav R Isola et al.
Journal of neurophysiology, 123(2), 815-830 (2020-01-23)
The interplay between inhibition and excitation can regulate behavioral expression and control, including the expression of communicative behaviors like birdsong. Computational models postulate varying degrees to which inhibition within vocal motor circuitry influences birdsong, but few studies have tested these

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