14-325
Rac/cdc42 Assay Reagent (PAK1 PBD, agarose), 300 µg
Specifically binds to & precipitates Rac-GTP & cdc42-GTP from cell lysates. For use in Affinity Binding Assays.
Sign Into View Organizational & Contract Pricing
All Photos(1)
UNSPSC Code:
12352200
eCl@ss:
32160405
NACRES:
NA.84
Recommended Products
biological source
human
Quality Level
manufacturer/tradename
Upstate®
technique(s)
affinity binding assay: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
Gene Information
human ... CDC42(998)
General description
GST fusion-protein, corresponding to the p21-binding domain (PBD, residues 67-150) of human PAK-1 provided bound to glutathione agarose.
Specifically binds to and precipitates Rac-GTP and cdc42-GTP from cell lysates.
Specifically binds to and precipitates Rac-GTP and cdc42-GTP from cell lysates.
Product Source: Human PAK-1, expressed in E. coli.
Quality
Routinely evaluated by Affinity Precipitation/Immunoblot Analysis
Storage and Stability
1 year at -20°C
Other Notes
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 2
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Cardiac remodeling caused by transgenic Over-expression of a corn rac gene.
Elnakish MT, Awad MM, Hassona MD, Alhaj MA, Kulkarni A, Citro LA, Sayyid M, Abouelnaga ZA et al.
American Journal of Physiology. Heart and Circulatory Physiology null
S H Chiang et al.
Nature, 410(6831), 944-948 (2001-04-20)
The stimulation of glucose uptake by insulin in muscle and adipose tissue requires translocation of the GLUT4 glucose transporter protein from intracellular storage sites to the cell surface. Although the cellular dynamics of GLUT4 vesicle trafficking are well described, the
Antioxidant N-acetylcysteine inhibits the activation of JNK3 mediated by the GluR6-PSD95-MLK3 signaling module during cerebral ischemia in rat hippocampus
Zhang, Quan-Guang, et al
Neuroscience Letters, 408, 159-164 (2006)
Akt inhibits MLK3/JNK3 signaling by inactivating Rac1: a protective mechanism against ischemic brain injury.
Quan-Guang Zhang, Xiao-Tian Wang, Dong Han, Xiao-Hui Yin, Guang-Yi Zhang, Tian-Le Xu
Journal of Neurochemistry null
Ccm1 Regulates Microvascular Morphogenesis during Angiogenesis.
Liu H, Rigamonti D, Badr A, Zhang J
Journal of Vascular Research null
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service