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Merck
CN

1.41352

SAFC

Polyvinyl alcohol

26-88, EMPROVE® ESSENTIAL, Ph. Eur., ChP, USP, JPE

Pharma Manufacturing

Synonym(s):

Poly(vinyl alcohol), PVA, PVOH

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About This Item

Linear Formula:
[-CH2CHOH-]n
CAS Number:
MDL number:
UNSPSC Code:
13111042

Agency

ChP
JPE
Ph. Eur.
USP

Quality Level

description

EMPROVE® ESSENTIAL Ph Eur,USP,JPE

product line

EMPROVE® ESSENTIAL

form

scales

technique(s)

API processing | nano-milling: suitable

mp

160-240 °C

application(s)

controlled release
liquid formulation
ophthalmics
pharmaceutical
semi-solid formulation
solid formulation

storage temp.

15-25°C

InChI

1S/C2H4O/c1-2-3/h2-3H,1H2

InChI key

IMROMDMJAWUWLK-UHFFFAOYSA-N

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General description

When working on a pharmaceutical formulation, there are specific considerations to make and challenging hurdles to take before you can successfully launch your final drug product - formulation stability, release kinetics and bioavailability limitations just to name a few. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Polyvinyl alcohol 26-88 is a synthetic, bio-compatible, toxicologically safe, and multi-compendial polymer. It is part of a portfolio spanning a wide range of pharmaceutical grade polyvinyl alcohols of different viscosities, hydrolysis grades and molecular weights and is well suited for a broad variety of pharmaceutical applications, including solid, liquid, and semi-solid formulations.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1


Certificates of Analysis (COA)

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Articles

PVA meets all the essential requirements to be used in ophthalmic preparations and offers important benefits compared to HPMC and CMC.

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