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Merck
CN

1.37036

SAFC

di-Sodium hydrogen phosphate dihydrate

EMPROVE® EXPERT, Ph. Eur., BP, USP

Pharma Manufacturing

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Synonym(s):
di-Sodium hydrogen phosphate dihydrate, Sodium monohydrogen phosphate, Sodium phosphate dibasic, sec-Sodium phosphate, Disodium hydrogen phosphate dihydrate, Disodium phosphate, Sodium phosphate dibasic dihydrate
Linear Formula:
Na2HPO4 · 2H2O
CAS Number:
Molecular Weight:
177.99
MDL number:
UNSPSC Code:
12352302
EC Index Number:
231-448-7

Agency

BP
Ph. Eur.
USP

Quality Level

description

EMPROVE® EXPERT Ph Eur,BP,USP

product line

EMPROVE® EXPERT

form

solid

feature

RNase and DNase free

pH

8.9-9.2 (5% in H2O)

mp

92.5 °C (Elimination of water of crystallisation)

solubility

93 g/L

density

2.1 g/cm3 at 20 °C

application(s)

liquid formulation
parenterals
pharma/biopharma processes
pharmaceutical

storage temp.

15-25°C

SMILES string

O.O.[Na+].[Na+].OP([O-])([O-])=O

InChI

1S/2Na.H3O4P.2H2O/c;;1-5(2,3)4;;/h;;(H3,1,2,3,4);2*1H2/q2*+1;;;/p-2

InChI key

KDQPSPMLNJTZAL-UHFFFAOYSA-L

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General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

di-Sodium hydrogen phosphate dihydrate is typically used as a phosphate buffer system component for biomolecule downstream chromatography steps or final liquid formulation.
Due to its low microbial and endotoxin limits, di-Sodium hydrogen phosphate dihydrate Emprove® Expert is especially suitable for high-risk applications.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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