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1.37018

SAFC

Sodium dihydrogen phosphate dihydrate

EMPROVE® EXPERT, Ph. Eur., BP, ChP, USP, JPE

Pharma Manufacturing

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Synonym(s):
Sodium phosphate monobasic dihydrate, mono-Sodium orthophosphate, Sodium biphosphate, Sodium phosphate monobasic, Sodium dihydrogen phosphate dihydrate
Linear Formula:
NaH2PO4 · 2H2O
CAS Number:
13472-35-0
Molecular Weight:
156.01
MDL number:
MFCD00149209
UNSPSC Code:
12352302
EC Index Number:
231-449-2

Agency

BP
ChP
JPE
Ph. Eur.
USP

Quality Level

500

product line

EMPROVE® EXPERT

form

solid

feature

RNase and DNase free

pH

4.5 (25 °C, 12 g/L in H2O)

mp

60 °C

density

1.915 g/cm3 at 20 °C

application(s)

liquid formulation
parenterals
pharma/biopharma processes
pharmaceutical

storage temp.

2-30°C

SMILES string

O.O.[Na+].OP(O)([O-])=O

InChI

1S/Na.H3O4P.2H2O/c;1-5(2,3)4;;/h;(H3,1,2,3,4);2*1H2/q+1;;;/p-1

InChI key

VBJGJHBYWREJQD-UHFFFAOYSA-M

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General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Sodium dihydrogen phosphate dihydrate is typically used as a phosphate buffer system component for downstream biomolecule chromatography steps or final liquid formulation.
Due to its low microbial and endotoxin limits, Sodium dihydrogen phosphate dihydrate Emprove® Expert is especially suitable for high-risk applications.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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