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Merck
CN

1.37003

SAFC

Citric acid monohydrate

crystalline, EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, USP

Synonym(s):

2-Hydroxypropane-1,2,3-tricarboxylic acid, Hydroxytricarballylic acid

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About This Item

Linear Formula:
HOC(COOH)(CH2COOH)2 · H2O
CAS Number:
Molecular Weight:
210.14
Beilstein:
4018641
MDL number:
UNSPSC Code:
12352106
EC Index Number:
201-069-1

Pricing and availability is not currently available.

Agency

BP
ChP
JP
Ph. Eur.
USP

Quality Level

vapor pressure

<1 Pa ( 25 °C)

description

cryst. EMPROVE® EXPERT Ph Eur,BP,ChP,JP,USP

product line

EMPROVE® EXPERT

form

crystalline
solid

feature

RNase and DNase free

impurities

endotoxins, low

pH

1.85 (25 °C, 50 g/L in H2O)

pKa 

(1) 3.13, (2) 4.76, (3) 6.4

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This Item
192420192400154903
甲醇 JIS special grade, &#8805;99.8%

192410

甲醇

甲醇 SAJ first grade, &#8805;99.5%

192420

甲醇

甲醇 SAJ special grade

192400

甲醇

甲醇 ACS spectrophotometric grade, &#8805;99.9%

154903

甲醇

assay

≥99.8%

assay

≥99.5%

assay

≥99.96% (GC)

assay

≥99.9%

form

liquid

form

liquid

form

liquid

form

liquid

bp

64.7 °C (lit.)

bp

64.7 °C (lit.)

bp

64.7 °C (lit.)

bp

64.7 °C (lit.)

expl. lim.

36 %

expl. lim.

36 %

expl. lim.

36 %

expl. lim.

36 %

mp

−98 °C (lit.)

mp

−98 °C (lit.)

mp

−98 °C (lit.)

mp

−98 °C (lit.)

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Citric acid anhydrous is typically used as a citrate buffer system component for biomolecule downstream chromatography steps or final liquid formulation.
Due to its low microbial and endotoxin limits, Citric acid anhydrous Emprove® Expert is especially suitable for high-risk applications.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

345.0 °F - closed cup

Flash Point(C)

173.9 °C - closed cup


  • What is the Emprove® Program?

    The Emprove® Program is a system providing comprehensive and thorough documentation of our filters and single-use components, pharma raw materials, and starting materials. Four document types are included with an Emprove® Program subscription:

    Material Qualification Dossier

    Free of charge - Sign in to download

    Quality Management Dossier (Open Access)

    Free of charge - Sign in to download

    Operational Excellence Dossier

    Available by subscription or for a fee

    Operational Excellence Dossier

    Available by subscription or for a fee

    Learn more about the benefits an Emprove® Program subscription can provide
    Why are these documents unavailable?
    Emprove® Dossiers contain information intended to support the registration process and risk assessment activities of pharmaceutical producers and contain confidential information. Please contact us if you would like access.

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