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Merck
CN

1.28202

SAFC

Sodium acetate anhydrous

EMPROVE® EXPERT, ChP, USP

Pharma Manufacturing

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Synonym(s):
Sodium acetate, Acetic acid sodium salt
Linear Formula:
CH3COONa
CAS Number:
Molecular Weight:
82.03
Beilstein:
3595639
MDL number:
UNSPSC Code:
51191566

grade

anhydrous

Quality Level

Agency

ChP
USP

product line

EMPROVE® EXPERT

form

solid
solid

autoignition temp.

1112 °F

mol wt

82.03 g/mol

impurities

endotoxins, low

pH

7.5-9.2 (20 °C, 30 g/L in H2O)

pKa 

4.76 (acetic acid)
4.76

bp

>400 °C (decomposition)

mp

>300 °C (dec.) (lit.)
324 °C (decomposition)

transition temp

flash point >250 °C

solubility

365 g/L

density

1.52 g/cm3 at 20 °C

application(s)

liquid formulation
pharma/biopharma processes
pharmaceutical

storage temp.

15-25°C

SMILES string

[Na+].CC([O-])=O

InChI

1S/C2H4O2.Na/c1-2(3)4;/h1H3,(H,3,4);/q;+1/p-1

InChI key

VMHLLURERBWHNL-UHFFFAOYSA-M

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Sodium acetate anhydrous is an acetate buffer system component commonly used in downstream biomolecule chromatography steps as well as liquid formulation.

Due to its low microbial and endotoxin limits, Sodium acetate anhydrous Emprove® Expert is especially suitable for high-risk applications.

Packaging

1282020003//3X1kg - plastic bottle
1282021001//1kg - plastic bottle
1282025001//5kg - plastic bottle
1282028012//12kg - plastic bucket
1282025026//25kg - plastic bucket

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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