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1.18488

SAFC

N-Acetyl-DL-tryptophan

greener alternative

EMPROVE® EXPERT, Ph. Eur., BP

Pharma Manufacturing

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Empirical Formula (Hill Notation):
C13H14N2O3
CAS Number:
87-32-1
Molecular Weight:
246.26
Beilstein:
89478
MDL number:
MFCD00005644
UNSPSC Code:
12352209
EC Index Number:
201-739-3

biological source

synthetic

Quality Level

500

Agency

BP
Ph. Eur.

product line

EMPROVE® EXPERT

form

crystalline

greener alternative product characteristics

Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product, Greener Alternative Product

impurities

low in endotoxins

mp

204-206 °C (dec.) (lit.)

application(s)

liquid formulation
parenterals
pharma/biopharma processes

greener alternative category

DfS-Developed, , DfS-Developed

storage temp.

10-30°C

SMILES string

CC(=O)NC(Cc1c[nH]c2ccccc12)C(O)=O

InChI

1S/C13H14N2O3/c1-8(16)15-12(13(17)18)6-9-7-14-11-5-3-2-4-10(9)11/h2-5,7,12,14H,6H2,1H3,(H,15,16)(H,17,18)

InChI key

DZTHIGRZJZPRDV-UHFFFAOYSA-N

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General description

Finding theright excipient that matches your needs as well as regulatory demands can be acomplicated challenge in formulation. With our application know-how andregulatory expertise, we support you in every step of development, scale-up,and production.As part of our Emprove® Program, our raw materials are offeredwith extensive documentation facilitating compliance of your pharma andbiopharma product, full supply chain transparency and risk mitigation. OurSAFC® portfolio of high-quality products for biopharmaceutical andpharmaceutical formulation and production withstands strict quality controlprocedures and is produced according to applicable cGMP guidelines.
We are committed to bringing you Greener Alternative Products, which belongs to one of the four categories of greener alternatives . This product is a Design for Sustainability (DfS) developed product. Click here to view its DfS scorecard.

Application

N-Acetyl-D,L-Tryptophanis widely used as a stabilizer in blood derived therapeutics.Due to its lowmicrobial and endotoxin limits, N-Acetyl-DL-tryptophan Emprove® Expert issuitable for high-risk applications.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

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Articles

Use of Stabilizers and Surfactants to Prevent Protein Aggregation

This article outlines critical factors in long-term stability of proteins, and how different stabilizers protect again mechanical and thermal stress.

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