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application(s)
detection
General description
Detection of the alkaline leukocyte phosphatase activity in leukocytes
LEUCOGNOST ALPA is used for detection of the alkaline leukocyte phospahatase activity in leukocytes. Alkaline leucocyte phosphatase (AP) catalyzes the hydrolysis of phosphate esters in alkaline solution. 1-naphthol released from 1-naphthylphosphate is coupled to a diazonium salt to form a brown azo dye, which is precipitated according to the locality and the AP activity in the cell. It is developed and registered as CE / IVD product for applications in diagnostics.The staining kit is sufficient for 12 stainings with up to 16 slides.
Analysis Note
Suitability for microscopy (Blood smear): passes test
Nuclei: blue
ALPA positive neutrophilic granulocytes: brown
Nuclei: blue
ALPA positive neutrophilic granulocytes: brown
Legal Information
LEUCOGNOST is a trademark of Merck KGaA, Darmstadt, Germany
Regulatory Information
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Certificates of Analysis (COA)
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