1.14894
Fractogel® EMD SE Hicap (M)
Synonym(s):
Fractogel® EMD SE Hicap (M)
About This Item
ligand
(Sulfoethyl)
Quality Level
description
strong cation exchanger, suspension in 20% ethanol and 150 mM NaCl (40-90 µm)
sterility
sterile (Caustic Stable)
product line
Fractogel®
form
resin
specific analyte(s)
MAbs
parameter
220 cm/hr flow rate
8 bar max. pressure
matrix active group
methacrylate
mean particle size
40-90 μm
capacity
160 mg binding capacity (lysozyme/ml of resin)
transition temp
flash point 35 °C (calculated)
application(s)
recombinant protein
vaccine development
separation technique
cation exchange
strong cation exchange
storage temp.
2-30°C
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General description
Features and Benefits
- Tentacle technology provides high yield, selectivity, and focused elution
- High loading capacity combined with high purity at lower elution volumes
- Compatibility with 2.5 % (v/v) aqueous benzyl alcohol containing 150 mM NaCl storage solution
Packaging
- 1.14894.0100: Fractogel® EMD SE Hicap (M) Resin 100ml
- 1.14894.0010: Fractogel® EMD SE Hicap (M) Resin 10ml
- 1.14894.0500: Fractogel® EMD SE Hicap (M) Resin 500ml
- 1.14894.5000: Fractogel® EMD SE Hicap (M) Resin 5L
Analysis Note
Microscopic evaluation: Uniform spherical particles,no agglomerates,no fines
Extractable matter (water): ≤ 0.08 %
Cerium: ≤ 20 µg/g
Pressure drop(column: ID=1.6 cm, L=10 cm at 5 ml/min): ≤ 1.0 bar
Particle size (d10): 37 - 45 µm
Particle size (d50): 48 - 60 µm
Particle size (d90): 63 - 77 µm
Colony forming units (TAMC + TYMC): ≤ 100 CFU/ml
Endotoxins: ≤ 1.00 EU/ml
Protein binding capacity (lysozyme): 120 - 160 mg/ml
Functional test (b:a): ≤ 0.20
Functional test: Separation of chymotrypsinogen A and lysozyme
Legal Information
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Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Flam. Liq. 3
WGK
WGK 3
Flash Point(F)
95.0 °F
Flash Point(C)
35 °C
Certificates of Analysis (COA)
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