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Merck
CN

1.11037

SAFC

tri-Sodium citrate

anhydrous, EMPROVE® ESSENTIAL, USP, FCC, E 331

Pharma Manufacturing

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Synonym(s):
tri-Sodium citrate
Empirical Formula (Hill Notation):
C6H5Na3O7
CAS Number:
Molecular Weight:
258.07
MDL number:
UNSPSC Code:
12352107
E Number:
E331
EC Index Number:
200-675-3

Agency

USP

Quality Level

reg. compliance

FCC

product line

EMPROVE® ESSENTIAL

form

solid

pH

7.5-9.0 (20 °C, 10 g/L in H2O)

mp

150 °C (decomposition)

solubility

425 g/L

density

1.76 g/cm3 at 18 °C

application(s)

liquid formulation
ophthalmics
pharmaceutical
semi-solid formulation
solid formulation

storage temp.

2-30°C

InChI

1S/C6H8O7.3Na/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;/q;3*+1/p-3

InChI key

HRXKRNGNAMMEHJ-UHFFFAOYSA-K

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

tri-Sodium citrate anhydrous is typically used as a citrate buffer system component for biomolecule downstream chromatography steps or final liquid formulation.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 1


Certificates of Analysis (COA)

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