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Safety Information

1.08114

Supelco

Tetrahydrofuran

≥99% (GC), EMPLURA®

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Synonym(s):
THF, Tetramethylene oxide, Oxolane, Butylene oxide, Butylene oxide, Oxolane, Tetramethylene oxide
Empirical Formula (Hill Notation):
C4H8O
CAS Number:
Molecular Weight:
72.11
Beilstein:
102391
MDL number:
UNSPSC Code:
12191504
EC Index Number:
203-726-8
NACRES:
NA.21

vapor density

2.5 (vs air)

Quality Level

vapor pressure

114 mmHg ( 15 °C)
143 mmHg ( 20 °C)

product line

EMPLURA®

Assay

≥99% (GC)

form

liquid

autoignition temp.

610 °F

expl. lim.

1.8-11.8 %

impurities

≤0.002% Free acid (as CH3COOH)
≤0.01% Peroxide (as H2O2)
≤0.1% Water

refractive index

n20/D 1.407 (lit.)

pH

7-8 (20 °C, 200 g/L in H2O)

bp

65-67 °C (lit.)

mp

−108 °C (lit.)

transition temp

flash point -21.5 °C

density

0.889 g/mL at 25 °C (lit.)

storage temp.

2-30°C

SMILES string

C1CCOC1

InChI

1S/C4H8O/c1-2-4-5-3-1/h1-4H2

InChI key

WYURNTSHIVDZCO-UHFFFAOYSA-N

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General description

EMPLURA® is our low-cost alternative to high-purity qualities. With EMPLURA we offer a range of solvents for a plurality of basic applications in non-regulated industries and for less demanding applications, preparative laboratory work and cleaning purposes. EMPLURA solvents provide adequate specifications with the most important parameters.

Application


  • Self-Assembly of Polyoxometalate-Based Nanoparticle Surfactants in Solutions: Highlights the use of Tetrahydrofuran as a critical solvent in the synthesis and self-assembly of polyoxometalate-based nanoparticles, exploring applications that could impact multiple fields including polymer research, drug delivery systems, and nanostructured materials (Xia et al., 2024).

  • Highly sensitive fluorescence turn-OFF and reversible chemical sensor for Hg(2+) ion based on pyrene appended 2-thiohydantoin: Tetrahydrofuran is used as a key solvent in the development of a novel fluorescence-based chemical sensor for mercury detection, demonstrating its application in environmental monitoring and safety in laboratory settings (Gawas et al., 2024).

  • Effect of Plasma pretreatment and Graphene oxide ratios on the transport properties of PVA/PVP membranes for fuel cells: This research employs Tetrahydrofuran as a processing solvent in the creation of polyvinyl alcohol/polyvinylpyrrolidone membranes enhanced with graphene oxide, focusing on improvements in ion transport for fuel cell applications (Abdel-Hamed et al., 2024).

  • Optimized Incorporation of Furan into Diketopyrrolopyrrole-Based Conjugated Polymers for Organic Field-Effect Transistors: Utilizes Tetrahydrofuran as a solvent to aid in the synthesis of novel conjugated polymers, potentially leading to advancements in organic electronics and polymer research (Neu et al., 2024).

Analysis Note

Purity (GC): ≥ 99.0 %
Identity (IR): conforms
Free acid (as CH₃COOH): ≤ 0.002 %
Density (d 20 °C/ 4 °C): 0.887 - 0.889
Peroxide (as H₂O₂): ≤ 0.01 %
Water: ≤ 0.1 %
Stabilized with 2,6-Di-tert-butyl-4-methylphenol (BHT)

Legal Information

EMPLURA is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Target Organs

Central nervous system, Respiratory system

Supplementary Hazards

WGK

WGK 1

Regulatory Information

危险化学品

Certificates of Analysis (COA)

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