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Supelco

Sodium dihydrogen phosphate monohydrate

for analysis EMSURE® ACS,Reag. Ph Eur

Synonym(s):

Sodium phosphate monobasic monohydrate, Monosodium phosphate, Sodium dihydrogen phosphate monohydrate

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About This Item

Linear Formula:
NaH2PO4 · H2O
CAS Number:
Molecular Weight:
137.99
MDL number:
UNSPSC Code:
12352302
EC Index Number:
231-449-2
NACRES:
NA.21

grade

ACS reagent

Quality Level

Agency

reag. Ph. Eur.

product line

EMSURE®

Assay

99.0-102.0% (alkalimetric)

form

crystals

potency

>2000 mg/kg LD50, oral (Rat)
>7940 mg/kg LD50, skin (Rabbit)

impurities

≤0.01% Insoluble matter

pH

4.1-4.5 (25 °C, 50 g/L in H2O)

solubility

850 g/L

density

2.04 g/cm3 at 20 °C

bulk density

880 kg/m3

anion traces

chloride (Cl-): ≤0.0005%
sulfate (SO42-): ≤0.003%

cation traces

Ca: ≤0.005%
Fe: ≤0.0005%
K: ≤0.005%
N: ≤0.001%
heavy metals: ≤0.0005%

UV absorption

λ: 280 nm Amax: ≤0.05

storage temp.

2-30°C

SMILES string

[Na+].[H]O[H].OP(O)([O-])=O

InChI

1S/Na.H3O4P.H2O/c;1-5(2,3)4;/h;(H3,1,2,3,4);1H2/q+1;;/p-1

InChI key

BBMHARZCALWXSL-UHFFFAOYSA-M

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Related Categories

Application


  • Development of a multiparticulate drug delivery system for in situ amorphisation.: This study explores the use of sodium dihydrogen phosphate monohydrate in developing a multiparticulate drug delivery system. The research highlights the compound′s role in achieving in situ amorphisation, enhancing drug solubility and bioavailability (Holm TP et al., 2022).

  • Metabolomic characterization of rhubarb species by capillary electrophoresis and ultra-high-pressure liquid chromatography.: Sodium dihydrogen phosphate monohydrate is utilized in the buffer system for capillary electrophoresis and UHPLC, aiding in the metabolomic analysis of rhubarb species. This research underscores its importance in improving separation efficiency and resolution in analytical methods (Tseng YJ et al., 2013).

Linkage

Replaces: SX0709; SX0709-5; SX0710; SX0710-1; SX0710-3; SX0710-5; SX0710-20

Analysis Note

Assay (alkalimetric): 99.0 - 102.0 %
Insoluble matter: ≤ 0.01 %
pH-value (5 %; water, 25 °C): 4.1 - 4.5
UV absorption (280 nm; 1 mol/l; 1 cm; water): ≤ 0.05
Chloride (Cl): ≤ 0.0005 %
Sulfate (SO₄): ≤ 0.003 %
Total nitrogen (N): ≤ 0.001 %
Heavy metals (ACS): ≤ 0.0005 %
Ca (Calcium): ≤ 0.005 %
Fe (Iron): ≤ 0.0005 %
K (Potassium): ≤ 0.005 %
Corresponds to ACS,Reag. Ph Eur

Legal Information

EMSURE is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Antonia E Schantl et al.
Nature communications, 11(1), 721-721 (2020-02-07)
Myo-inositol hexakisphosphate (IP6) is a natural product known to inhibit vascular calcification (VC), but with limited potency and low plasma exposure following bolus administration. Here we report the design of a series of inositol phosphate analogs as crystallization inhibitors, among

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