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Merck
CN

1.06290

SAFC

Sodium benzoate

EMPROVE® EXPERT, Ph. Eur., BP, ChP, NF, JP, FCC, E 211

Pharma Manufacturing

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Synonym(s):
Sodium benzoate
Empirical Formula (Hill Notation):
C7H5NaO2
CAS Number:
Molecular Weight:
144.10
MDL number:
UNSPSC Code:
12352107
E Number:
E211
EC Index Number:
208-534-8

Agency

BP
ChP
JP
NF
Ph. Eur.

Quality Level

reg. compliance

FCC

product line

EMPROVE® EXPERT

form

solid

autoignition temp.

>500 °C

pH

8 (20 °C, 100 g/L in H2O)

mp

436 °C

density

1.50 g/cm3 at 20 °C

application(s)

liquid formulation
parenterals
pharmaceutical
semi-solid formulation
solid formulation

storage temp.

2-25°C

InChI

1S/C7H6O2.Na/c8-7(9)6-4-2-1-3-5-6;/h1-5H,(H,8,9);/q;+1/p-1

InChI key

WXMKPNITSTVMEF-UHFFFAOYSA-M

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General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Sodium benzoate is commonly used as a preservative in pharmaceutical formulations and cosmetics. It is also used as additive for the preservation of food.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Articles

Find key considerations for the selection and use of benzalkonium chloride, benzyl alcohol, benzaldehyde, parabens, benzoic acid, and sodium benzoate as preservatives.

Find key considerations for the selection and use of preservatives in a range of different therapeutic applications including topical, oral, transmucosal, inhalation, and otic, as well as injectables.

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