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Merck
CN

1.05995

SAFC

(-)-Menthol

EMPROVE® ESSENTIAL, Ph. Eur., BP, JP, USP

Pharma Manufacturing

Synonym(s):

(-)-Menthol, 2-Isopropyl-5-methylcyclohexanol

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About This Item

Empirical Formula (Hill Notation):
C10H20O
CAS Number:
Molecular Weight:
156.27
MDL number:
UNSPSC Code:
12352104
EC Index Number:
218-690-9

Agency

BP
JP
Ph. Eur.
USP

Quality Level

description

EMPROVE® ESSENTIAL Ph Eur,BP,JP,USP

product line

EMPROVE® ESSENTIAL

form

solid

potency

3300 mg/kg LD50, oral (Rat)
>5000 mg/kg LD50, skin (Rabbit)

bp

216 °C/1013 hPa

mp

41-44 °C

transition temp

flash point 101 °C

solubility

490 mg/L

density

0.890 g/cm3 at 20 °C

application(s)

pharmaceutical
semi-solid formulation
solid formulation

storage temp.

15-25°C

InChI

1S/C10H20O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-11H,4-6H2,1-3H3/t8-,9+,10-/m1/s1

InChI key

NOOLISFMXDJSKH-KXUCPTDWSA-N

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Menthol is a commonly used ingredient in food and pharmaceutical applications. In pharmaceutical applications, menthol has been used primarily for oral dosage forms.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

WGK

WGK 1

Flash Point(F)

201.2 °F

Flash Point(C)

94 °C


Certificates of Analysis (COA)

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