1.01695
Benzonase®
suitable for biopharmaceutical production EMPROVE® bio
Pharma Manufacturing
Recommended Products
biological source
Serratia marcescens
Quality Level
recombinant
expressed in E. coli
product line
EMPROVE® Bio
Assay
≥99% (SDS-PAGE)
form
buffered aqueous glycerol solution
concentration
≥250 units/μL
pH
8.0 (25 °C in H2O)
application(s)
pharma/biopharma processes
shipped in
dry ice
storage temp.
-10 to -25°C
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General description
Benzonase® endonuclease is the smart solution for DNA removal in viral vaccine and viral vector production and has proven its value for over 30 years. Balancing efficiency and regulatory compliance by delivering reliability and high-quality due manufacturing under good manufacturing practices (GMP ICH Q7). Our extensive documentation packages of Emprove® dossiers and the availability of a FDA Drug Master File type II, supports you in filing your vaccine manufacturing process to the authorities.
M-Clarity Program
As part of our EMPROVE® Program, our raw materials are offered with EMPROVE® Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.
Our comprehensive portfolio of downstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.
Application
Biochem/physiol Actions
Legal Information
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WGK
WGK 1
Certificates of Analysis (COA)
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Articles
Benzonase®endonuclease efficiently removes nucleic acid contaminants from viral production, crucial for cell and gene therapies and vaccines.
This technical article breaks down the steps of upstream and downstream bioprocessing and formulation of virus-like particle vaccines.
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