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1.00805

SAFC

Titanium(IV) oxide

EMPROVE® ESSENTIAL, Ph. Eur., BP, ChP, JP, USP, E 171

Pharma Manufacturing

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Synonym(s):
Titanium(IV) oxide, Titanic anhydride, Titanium dioxide
Empirical Formula (Hill Notation):
O2Ti
CAS Number:
13463-67-7
Molecular Weight:
79.87
MDL number:
MFCD00011269
UNSPSC Code:
12352303
E Number:
E171
EC Index Number:
236-675-5

Agency

BP
ChP
JP
Ph. Eur.
USP

Quality Level

500

product line

EMPROVE® ESSENTIAL

form

fine powder

particle size

~0.8 μm (d50)

pH

7-8 (20 °C, 100 g/L in H2O, slurry)

bp

2900 °C/1013 hPa

mp

1855 °C

application(s)

pharmaceutical
semi-solid formulation
solid formulation

storage temp.

2-30°C

InChI

1S/2O.Ti

InChI key

GWEVSGVZZGPLCZ-UHFFFAOYSA-N

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General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Titanium(IV) oxide is a commonly used ingredient in both food and pharmaceuticals. In pharmaceutical applications, Titanium(IV) oxide has been used primarily for solid oral dosage forms as a white pigment.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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