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1.00802

SAFC

L(+)-Tartaric acid

crystalline, EMPROVE® ESSENTIAL, Ph. Eur., BP, ChP, JP, NF, E 334

Pharma Manufacturing

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Synonym(s):
L(+)-Tartaric acid, 2,3-Dihydroxybutanedioic acid
Linear Formula:
HOOCCH(OH)CH(OH)COOH
CAS Number:
87-69-4
Molecular Weight:
150.09
MDL number:
MFCD00064207
UNSPSC Code:
12352106
E Number:
E334
EC Index Number:
201-766-0

Agency

BP
ChP
JP
NF
Ph. Eur.

Quality Level

500

vapor pressure

<5 Pa ( 20 °C)

product line

EMPROVE® ESSENTIAL

Assay

99.7-100.5% dry basis (acidimetric)

form

coarse powder
crystalline

autoignition temp.

425 °C

pH

1.6 (25 °C, 100 g/L in H2O)

mp

168-170 °C

transition temp

flash point 210 °C

solubility

water: 1390 g/L at 20 °C

density

1.76 g/cm3 at 20 °C

cation traces

As: ≤0.0001%
Ca: ≤0.0200%
Ca:, passes test
Hg: ≤0.0001%
Pb: ≤0.0002%
heavy metals (as Pb): ≤0.0010%

application(s)

liquid formulation
pharmaceutical
semi-solid formulation
solid formulation

storage temp.

2-30°C

InChI

1S/C4H6O6/c5-1(3(7)8)2(6)4(9)10/h1-2,5-6H,(H,7,8)(H,9,10)

InChI key

FEWJPZIEWOKRBE-UHFFFAOYSA-N

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General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Tartaric acid is a commonly used ingredient in both food and pharmaceutics. In pharmaceutical applications, tartaric acid has been used primarily as a pH modifier, and in the production of effervescent formulations.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H318

Precautionary Statements

P280 - P305 + P351 + P338

Hazard Classifications

Eye Dam. 1

WGK

WGK 1

Flash Point(F)

302.0 °F

Flash Point(C)

150 °C

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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