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SAFC

Adipic acid

EMPROVE® ESSENTIAL, Ph. Eur., NF

Pharma Manufacturing

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Synonym(s):
Adipic acid, Hexanedioic acid
Empirical Formula (Hill Notation):
C6H10O4
CAS Number:
124-04-9
Molecular Weight:
146.14
MDL number:
MFCD00004420
UNSPSC Code:
12352106
E Number:
E355
EC Index Number:
204-673-3

Agency

NF
Ph. Eur.

Quality Level

500

reg. compliance

FCC

vapor pressure

0.097 hPa ( 18.5 °C)

description

EMPROVE® ESSENTIAL Ph Eur,NF,FCC,E 355

product line

EMPROVE® ESSENTIAL

form

solid

autoignition temp.

405 °C

potency

5700 mg/kg LD50, oral (Rat)
>7940 mg/kg LD50, skin (Rabbit)

technique(s)

API processing | cocrystal formation: suitable
API processing | salt formation: suitable

pH

2.7 (25 °C, 23 g/L in H2O)

mp

150.9 °C

transition temp

flash point 196 °C

solubility

15 g/L

density

1.36 g/cm3 at 25 °C

application(s)

liquid formulation
pharmaceutical
solid formulation

storage temp.

15-25°C

InChI

1S/C6H10O4/c7-5(8)3-1-2-4-6(9)10/h1-4H2,(H,7,8)(H,9,10)

InChI key

WNLRTRBMVRJNCN-UHFFFAOYSA-N

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General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Adipic acid is typically used as a pH modifier in pharmaceutical applications.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H318

Precautionary Statements

P280 - P305 + P351 + P338

Hazard Classifications

Eye Dam. 1

WGK

WGK 1

Flash Point(F)

closed cup

Flash Point(C)

closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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