09-101
Anti-cGMP (cyclic GMP) Antibody
serum, Upstate®
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Synonym(s):
Guanosine 3′, 5′-cyclic monophosphate
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity (predicted by homology)
all
manufacturer/tradename
Upstate®
technique(s)
ELISA: suitable
immunohistochemistry: suitable
radioimmunoassay: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... PRKG1(5592)
Specificity
Recognizes cGMP. Very little cross reactivity to cAMP based on ELISA.
Immunogen
2 Monosuccinyl cyclic GMP conjugated to KLH
Application
Anti-cGMP (cyclic GMP) Antibody detects level of cGMP (cyclic GMP) & has been published & validated for use in ELISA, IH, RIA.
Research Category
Signaling
Signaling
Research Sub Category
GPCR, cAMP/cGMP & Calcium Signaling
GPCR, cAMP/cGMP & Calcium Signaling
Quality
Routinely evaluated by ELISA
Physical form
Serum
Storage and Stability
2 years at -20°C from date of shipment
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 1
Certificates of Analysis (COA)
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Chongyang Zhang et al.
Journal of the American Heart Association, 11(2), e023053-e023053 (2022-01-06)
Background cGMP-hydrolyzing phosphodiesterase type 5 (PDE5) regulates vascular smooth muscle cell (SMC) contraction by antagonizing cGMP-dependent protein kinase I (PKGI)-dependent SMC relaxation. SMC contractile dysfunction is implicated in the pathogenesis of aortic aneurysm. PDE5 inhibitors have been used for treating
Susanne Vogeler et al.
BMC developmental biology, 20(1), 23-23 (2020-11-25)
Nitric oxide (NO) is presumed to be a regulator of metamorphosis in many invertebrate species, and although NO pathways have been comparatively well-investigated in gastropods, annelids and crustaceans, there has been very limited research on the effects of NO on
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