07-373
Anti-acetyl-Histone H2B Antibody
Upstate®, from rabbit
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250 ML
CN¥2,105.25
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250 ML
CN¥2,105.25
About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
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This Item | I8507 | 193510 | 5S06052 |
|---|---|---|---|
| vapor pressure 24.09 psi ( 55 °C) | vapor pressure 24.09 psi ( 55 °C), 7.89 psi ( 20 °C) | vapor pressure 24.09 psi ( 55 °C), 7.89 psi ( 20 °C) | vapor pressure - |
| assay ≥99.0% (GC) | assay 99% | assay ≥93.0% | assay - |
| form liquid | form liquid | form liquid | form - |
| potency 79.84 mg/kg LD50, oral (rat) | potency - | potency - | potency - |
| expl. lim. 8.5-66 % (v/v) | expl. lim. - | expl. lim. - | expl. lim. - |
Specificity
acetylated Histone H2B
Immunogen
Synthetic peptide in which there is an acetyl-lysine at residues 5, 12, 15 and 20 of human Histone H2B
Application
Detect acetyl-Histone H2B also known as Histone H2B with Anti-acetyl-Histone H2B Antibody (Rabbit Polyclonal Antibody), that has been demonstrated to work in WB.
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Histones
Histones
Quality
routinely evaluated by immunoblot in sodium butyrate treated, acid extracted proteins from HeLa cells
Target description
15 kDa
Physical form
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
Protein A chromatography
Storage and Stability
2 years at -20°C
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Spatial memory consolidation is associated with induction of several lysine-acetyltransferase (histone acetyltransferase) expression levels and H2B/H4 acetylation-dependent transcriptional events in the rat hippocampus.
Bousiges, O; Vasconcelos, AP; Neidl, R; Cosquer, B; Herbeaux, K; Panteleeva, I; Loeffler et al.
Neuropsychopharmacology null
Snehajyoti Chatterjee et al.
EMBO molecular medicine, 10(11) (2018-10-03)
Chromatin acetylation, a critical regulator of synaptic plasticity and memory processes, is thought to be altered in neurodegenerative diseases. Here, we demonstrate that spatial memory and plasticity (LTD, dendritic spine formation) deficits can be restored in a mouse model of
A novel activator of CBP/p300 acetyltransferases promotes neurogenesis and extends memory duration in adult mice.
Chatterjee, S; Mizar, P; Cassel, R; Neidl, R; Selvi, BR; Mohankrishna, DV; Vedamurthy et al.
The Journal of Neuroscience null
Lucie Crouzier et al.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 39, 29-45 (2020-09-08)
The sigma-1 receptor (S1R) is a membrane-associated protein expressed in neurons and glia at mitochondria-associated endoplasmic reticulum (ER) membranes (MAMs). S1R interacts with different partners to regulate cellular responses, including ER stress, mitochondrial physiology and Ca2+ fluxes. S1R shapes cellular
Frederick A Schroeder et al.
PloS one, 8(8), e71323-e71323 (2013-08-24)
Psychiatric diseases, including schizophrenia, bipolar disorder and major depression, are projected to lead global disease burden within the next decade. Pharmacotherapy, the primary--albeit often ineffective--treatment method, has remained largely unchanged over the past 50 years, highlighting the need for novel
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