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Sigma-Aldrich

Anti-mGluR7 Antibody

Upstate®, from rabbit

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Synonym(s):
Anti-GLUR7, Anti-MGLU7, Anti-MGLUR7, Anti-NEDSHBA, Anti-PPP1R87
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

purified antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... GRM7(2917)

Specificity

mGluR7

Immunogen

peptide (C-NSPAAKKKYVSYNN) corresponding to amino acids 899-912 of human mGluR7

Application

Detect mGluR7 using this Anti-mGluR7 Antibody validated for use in WB.
Research Category
Neuroscience
Research Sub Category
Vesicular Trafficking

Neurodegenerative Diseases

Quality

routinely evaluated by immunoblot on rat brain microsomal preparation

Target description

97kDa

Physical form

0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
Protein A chromatography

Storage and Stability

2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

WGK

WGK 1


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Tevye Jason Stachniak et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 41(39), 8150-8162 (2021-08-13)
Throughout development, neuronal identity is controlled by key transcription factors that determine the unique properties of a cell. During embryogenesis, the transcription factor Prox1 regulates VIP-positive cortical interneuron migration, survival, and connectivity. Here, we explore the role of Prox1 as
GluR7 is an essential subunit of presynaptic kainate autoreceptors at hippocampal mossy fiber synapses.
Paulo S Pinheiro, David Perrais, Francoise Coussen, Jacques Barhanin, Bernhard Bettler et al.
Proceedings of the National Academy of Sciences of the USA null
Katarzyna Rogoz et al.
Cell reports, 14(2), 370-379 (2016-01-11)
Allergic reactions can in severe cases induce a state of circulatory shock referred to as anaphylaxis. Histamine, the primary mediator of this condition, is released from immune cells, and, therefore, anaphylaxis has so far been considered an immune system disorder.
Nicole M Fisher et al.
JCI insight, 6(4) (2021-01-22)
The metabotropic glutamate receptor 7 (mGlu7) is a G protein-coupled receptor that has been recently linked to neurodevelopmental disorders. This association is supported by the identification of GRM7 variants in patients with autism spectrum disorder, attention deficit hyperactivity disorder, and
Anna Bodzęta et al.
Molecular biology of the cell, 33(8), ar66-ar66 (2022-05-06)
Presynaptic metabotropic glutamate receptors (mGluRs) are essential for the control of synaptic transmission. However, how the subsynaptic dynamics of these receptors is controlled and contributes to synaptic signaling remain poorly understood quantitatively. Particularly, since the affinity of individual mGluR subtypes

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