All Photos(1)
Synonym(s):
Anti-GADS, Anti-GRAP-2, Anti-GRB2L, Anti-GRBLG, Anti-GRID, Anti-GRPL, Anti-GrbX, Anti-Grf40, Anti-Mona, Anti-P38
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
biological source
rabbit
Quality Level
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human, mouse
manufacturer/tradename
Upstate®
technique(s)
immunoprecipitation (IP): suitable
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... GRAP2(9402)
Specificity
GADS
Immunogen
KLH-conjugated, synthetic peptide corresponding to amino acids 174-188 of murine GADS (GEEIRPSVNRKLSDH)
Application
Anti-GADS Antibody is an antibody against GADS for use in IP & WB.
Quality
routinely evaluated by immunoblot on Jurkat RIPA cell lysate
Target description
40kDa
Physical form
Format: Purified
Analysis Note
Control
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Hematopoietic progenitor kinase 1 negatively regulates T cell receptor signaling and T cell-mediated immune responses.
Jr-Wen Shui, Jonathan S Boomer, Jin Han, Jun Xu, Gregory A Dement, Guisheng Zhou, Tse-Hua Tan
Nature Immunology null
Eri Ishikawa et al.
Nature communications, 7, 12756-12756 (2016-09-28)
Thymic selection shapes an appropriate T cell antigen receptor (TCR) repertoire during T cell development. Here, we show that a serine/threonine kinase, protein kinase D (PKD), is crucial for thymocyte positive selection. In T cell-specific PKD-deficient (PKD2/PKD3 double-deficient) mice, the
Quantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor-independent TCR signaling hub.
Roncagalli, R; Hauri, S; Fiore, F; Liang, Y; Chen, Z; Sansoni, A; Kanduri, K; Joly et al.
Nature Immunology null
Luminal leptin inhibits L-glutamine transport in rat small intestine: involvement of ASCT2 and B0AT1.
Ducroc R, Sakar Y, Fanjul C, Barber A, Bado A, Lostao MP
American Journal of Physiology: Gastrointestinal and Liver Physiology null
Juris A Grasis et al.
Molecular and cellular biology, 30(14), 3596-3609 (2010-05-12)
In vitro data have suggested that activation of the inducible T-cell kinase (ITK) requires an interaction with the adaptor protein SLP-76. One means for this interaction involves binding of the ITK SH3 domain to the polyproline-rich (PR) region of SLP-76.
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