06-661
Anti-Calreticulin Antibody
Upstate®, from rabbit
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UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
pig, human, mouse, Xenopus, bovine, rat
manufacturer/tradename
Upstate®
technique(s)
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... CALR(811)
Specificity
calreticulin; does not cross react with other endoplasmic reticulum proteins
Immunogen
peptide (QAKDEL) corresponding to the C-terminus (amino acids 412-417) of human calreticulin
Application
Anti-Calreticulin Antibody is an antibody against Calreticulin for use in IC, IH & WB.
Research Sub Category
PI3K, Akt, & mTOR Signaling
Enzymes & Biochemistry
PI3K, Akt, & mTOR Signaling
Enzymes & Biochemistry
Quality
routinely evaluated by immunoblot on RIPA lysates from murine 3T3/NIH fibroblasts
Target description
60kDa
Linkage
Replaces: MABT145
Physical form
0.1M Tris-glycine, pH 7.0, 0.15M NaCl and 0.05% sodium azide.
Format: Purified
Analysis Note
Control
Positive Antigen Control: Catalog #12-305, 3T3/A31 lysate. Add 2.5 μL of 2-mercapto-ethanol/100 μL of lysate and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced lysate per lane for minigels.
Positive Antigen Control: Catalog #12-305, 3T3/A31 lysate. Add 2.5 μL of 2-mercapto-ethanol/100 μL of lysate and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced lysate per lane for minigels.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
recommended
Product No.
Description
Pricing
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Maria L Valencik et al.
Circulation research, 99(12), 1403-1410 (2006-11-11)
Integrins mechanically link the cytoskeleton to the extracellular matrix in cardiac myocytes and are thereby involved in mechanotransduction. Integrins appear to be necessary for cardiac myocyte hypertrophy. To determine the effect of increased integrin ligation and signaling on adult cardiac
M Waser et al.
The Journal of cell biology, 138(3), 547-557 (1997-08-11)
We have isolated and characterized a 12-kb mouse genomic DNA fragment containing the entire calreticulin gene and 2.14 kb of the promoter region. The mouse calreticulin gene consists of nine exons and eight introns, and it spans 4.2 kb of
Endoplasmic reticulum form of calreticulin modulates glucocorticoid-sensitive gene expression.
Michalak, M, et al.
The Journal of Biological Chemistry, 271, 29436-29445 (1996)
Calreticulin inhibits glucocorticoid- but not cAMP-sensitive expression of tyrosine aminotransferase gene in cultured McA-RH7777 hepatocytes.
Burns, K, et al.
Molecular and Cellular Biochemistry, 171, 37-43 (1997)
Takashi Tajima et al.
Proteomes, 7(2) (2019-04-13)
Myxoid liposarcoma (MLS) is a mesenchymal malignancy. To identify innovate seeds for clinical applications, we examined the proteomes of primary tumor tissues from 10 patients with MLS with different statuses of postoperative metastasis. The protein expression profiles of tumor tissues
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