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Merck
CN

06-127

Anti-PDGF Antibody, neutralizing

Upstate®, from goat

Synonym(s):

Anti-PDGF-A, Anti-PDGF1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Key Documents

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Product Name

Anti-PDGF Antibody, neutralizing, Upstate®, from goat

biological source

goat

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

bovine, pig, mouse, human

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

NM_016205
NM_033016
NM_033023

UniProt accession no.

P01127
P04085

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... PDGFA(5154)

Application

Anti-PDGF Antibody, neutralizing detects level of PDGF & has been published & validated for use in WB.
Research Category
Signaling
Research Sub Category
Growth Factors & Receptors

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

14/16 kDa

Immunogen

Purified human PDGF-AB; recognizes PDGF AA, AB and BB.

Physical form

DEAE chromatography
Format: Purified

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Polypeptide growth factors: roles in normal and abnormal cell growth.
Deuel, T F
Annual Review of Cell Biology, 3, 443-492 (1987)
Jamie L Wilson et al.
Current topics in peptide & protein research, 16, 1-17 (2015-01-01)
Migration of vascular smooth muscle cells is a key element in remodeling during pulmonary arterial hypertension (PAH). We are observing key alterations in the migratory characteristics of human pulmonary artery smooth muscle cells (HPASMC) isolated from transplanted lungs of subjects
Platelet-derived growth factor receptor regulates salivary gland morphogenesis via fibroblast growth factor expression.
Shinya Yamamoto,Emiko Fukumoto,Keigo Yoshizaki,Tsutomu Iwamoto,Aya Yamada,Kojiro Tanaka et al.
The Journal of Biological Chemistry null
Structure and function of platelet-derived growth factor (PDGF) and related proteins.
Hannink, M and Donoghue, D J
Biochimica et Biophysica Acta, 989, 1-10 (1989)
A Görlach et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 14(11), 1518-1528 (2000-08-06)
Vascular injury after balloon angioplasty results in the rapid activation of platelets leading to the release of growth factors and vasoactive substances. In addition, up-regulation of tissue factor (TF) and an increased production of reactive oxygen species (ROS) have been
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