06-1091
Anti-IL-13 receptor Antibody, alpha-2 (IL-13RA2)
from rabbit, purified by affinity chromatography
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Synonym(s):
interleukin 13 receptor, alpha 2, interleukin-13 receptor subunit alpha-2, interleukin 13 receptor alpha 2 chain, Interleukin-13-binding protein, IL-13R subunit alpha-2, cancer/testis antigen 19, IL-13 receptor subunit alpha-2, interleukin 13 binding pro
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human
technique(s)
immunohistochemistry: suitable (paraffin)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... IL13RA2(3598)
General description
Interleukin-13 receptor subunit alpha-2 (IL-13RA2) is one receptor of Interleukin-13 which is a key moderator of asthma and allergic inflammation. IL-13 and its receptors have been shown to play a part in alcohol-mediated activation of pro-fibrotic pathways. IL-13 has a suppressive effect on macrophage activation but cannot activate T cells.
Specificity
This antibody recognizes Interleukin-13 receptor, alpha-2 at the cytoplasmic domain.
Immunogen
Epitope: Cytoplasmic Domain
KLH-conjugated linear peptide corresponding to human Interleukin-13 receptor, alpha-2 at the cytoplasmic domain.
Application
Anti-IL-13 receptor Antibody, alpha-2 (IL-13RA2) is an antibody against IL-13 receptor for use in WB, IH(P).
Research Category
Inflammation & Immunology
Inflammation & Immunology
Research Sub Category
Cytokines & Cytokine Receptors
Cytokines & Cytokine Receptors
Western Blot (SNAP i.d. Protein Detection System) Analysis: 5 µg/mL from a previous lot detected Interleukin-13 receptor, alpha-2 in 10 µg of HeLa cell lysate.
Immunohistochemistry (paraffin) Analysis: A 1:500 dilution from a previous lot was used to detect Interleukin-13 receptor, alpha-2 in colorectal carcinoma and normal human kidney/medulla tissue sections.
Immunohistochemistry (paraffin) Analysis: A 1:500 dilution from a previous lot was used to detect Interleukin-13 receptor, alpha-2 in colorectal carcinoma and normal human kidney/medulla tissue sections.
Quality
Evaluated by Western Blot in HeLa cell lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected Interleukin-13 receptor, alpha-2 in 10 µg of HeLa cell lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected Interleukin-13 receptor, alpha-2 in 10 µg of HeLa cell lysate.
Target description
~44 kDa observed
Physical form
Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control
HeLa cell lysate
HeLa cell lysate
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Yang Zhou et al.
The Journal of clinical investigation, 125(8), 3178-3192 (2015-06-30)
Hermansky-Pudlak syndrome (HPS) comprises a group of inherited disorders caused by mutations that alter the function of lysosome-related organelles. Pulmonary fibrosis is the major cause of morbidity and mortality in patients with subtypes HPS-1 and HPS-4, which both result from
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