05-855R
Anti-GluR1 Antibody, Recombinant, rabbit monoclonal
Upstate®, from rabbit
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Anti-GluA1, Anti-GluR-1, Anti-GluR-A, Anti-GluR-K1, Anti-GluR1
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biological source
rabbit
Quality Level
antibody form
purified antibody
antibody product type
primary antibodies
clone
monoclonal
species reactivity
rat, mouse
manufacturer/tradename
Upstate®
technique(s)
immunohistochemistry: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
mouse ... Gria1(14799)
rat ... Gria1(50592)
Specificity
Cat. # 05-855R recognizes the monomer and dimer of GluR1.
Reactivity with other species has not been determined.
Application
Anti-GluR1 Antibody, Recombinant is an antibody against GluR1 for use in WB, IH.
Immunohistochemistry: Cat. # 05-855R can detect GluR1 in rat brain tissue at 1:250 dilution.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Neurotransmitters & Receptors
Quality
Routinely evaluated by western blot on rat brain microsomal lysate.
Target description
Monomer at 106 kDa and Dimer at 200 kDa
Physical form
Format: Purified
Purified Antibody in 0.01M Tris-Glycine, 0.15M NaCl, pH 7.4, 0.05% NaN3with 40% glycerol.
Storage and Stability
Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.
Analysis Note
Control
Rat brain microsomal lysate
Rat brain microsomal lysate
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
recommended
Product No.
Description
Pricing
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Central amygdala GluA1 facilitates associative learning of opioid reward.
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GluA1 in central amygdala increases pain but inhibits opioid withdrawal-induced aversion.
Molecular pain, 16, 1744806920911543-1744806920911543 (2020-03-13)
Astrocytic NMDA Receptors in the Basolateral Amygdala Contribute to Facilitation of Fear Extinction.
The international journal of neuropsychopharmacology, 24(11), 907-919 (2021-08-08)
Enhancement of N-methyl-D-aspartate (NMDA) receptor function using glycine-site agonist D-cycloserine is known to facilitate fear extinction, providing a means to augment cognitive behavioral therapy in anxiety disorders. A novel class of glycine-site agonists has recently been identified, and we have
The Journal of biological chemistry, 298(8), 102245-102245 (2022-07-15)
Cortical glutamate and midbrain dopamine neurotransmission converge to mediate striatum-dependent behaviors, while maladaptations in striatal circuitry contribute to mental disorders. However, the crosstalk between glutamate and dopamine signaling has not been entirely elucidated. Here we uncover a molecular mechanism by
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
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