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Sigma-Aldrich

Anti-Amyloid β (Aβ)x-40 Antibody, clone 11A5-B10

ascites fluid, clone 11A5-B10, Upstate®

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UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

antibody form

ascites fluid

antibody product type

primary antibodies

clone

11A5-B10, monoclonal

species reactivity

human, mouse

manufacturer/tradename

Upstate®

technique(s)

immunohistochemistry: suitable
western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

Gene Information

human ... APP(351)

Specificity

Amyloid βx-40 polypeptide

Immunogen

peptide corresponding to amino acids 34-40 of human Amyloid βx-40 peptide

Application

Detect Amyloid β (Aβ)x-40 using this Anti-Amyloid β (Aβ)x-40 Antibody, clone 11A5-B10 validated for use in WB, IH.

Quality

routinely evaluated by immunoblot on of synthetic Amyloid βx-40 polypeptide

Target description

~4.5kDa

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

nwg


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Céline Vrancx et al.
Molecular neurobiology, 58(12), 6647-6669 (2021-10-06)
The β-amyloid peptide (Aβ) is found as amyloid fibrils in senile plaques, a typical hallmark of Alzheimer's disease (AD). However, intermediate soluble oligomers of Aβ are now recognized as initiators of the pathogenic cascade leading to AD. Studies using recombinant
Yuta Takaichi et al.
Acta neuropathologica communications, 9(1), 10-10 (2021-01-09)
Alzheimer's disease (AD) is characterized by the accumulation of amyloid-β (Aβ) as senile plaques and cerebral amyloid angiopathy, and hyperphosphorylated tau (hp-tau) as neurofibrillary tangles in the brain. The AD-related pathology has been reported in several non-human animals, and most

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